315 464-7664

Vladimir Kuznetsov, PhD

韦斯科顿大厅1271号

欧文大道766号

锡拉丘兹，纽约州13210

Vladimir Kuznetsov's email address generated as an image

当前预约

教授泌尿外科

教授 Biochemistry and Molecular Biology

语言

英语

俄罗斯

WEB资源

Jenjaroenpun P, Kuznetsov VA. TTS mapping: integrative WEB tool for analysis of triplex formation target DNA sequences, G-quadruplets and non-protein coding regulatory DNA elements in the human genome. BMC基因组学. 2009 Dec 3;10 Suppl 3:S9.

Wongsurawat T, Woo CC, Giannakakis A, ..., Kuznetsov VA, Sorokin V. Distinctive molecular signature and activated signaling pathways in aortic smooth muscle cells of patients with myocardial infarction. 动脉粥样硬化. 2018年4月;271:237 - 244.

Wang J, Jenjaroenpun P, Bhinge A, Angarica VE, Del Sol A, Nookaew I, Kuznetsov VA, Stanton LW. Single-cell gene expression analysis reveals regulators of distinct cell subpopulations among developing human neurons. 基因组Res. 2017 Nov;27(11):1783-1

Predictive tool to identify sequences causing mutations, genome instability and diseases

陈L,..., Kuznetsov VA, Thiery JP. Transposon insertional mutagenesis in mice identifies human 乳腺癌 susceptibility genes and signatures for stratification. Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):E2215-E2224.

R-loop数据库

QmRLFS-finder: a model, web server and stand-alone tool for prediction and analysis of R-loop forming sequences

哎哟,克. S. 库兹涅佐夫，V. A. Big genomics and clinical data analytics strategies for precision cancer prognosis. Sci. 代表. 6, 36493

Genomic Data Improves Breast Cancer Diagnosis & Treatment Read more from Asian Scientist Magazine

Grinchuk OV, Yenamandra SP,..., Chow PK,Kuznetsov VA. Tumor-adjacent tissue co-expression profile analysis reveals pro-oncogenic ribosomal gene signature for prognosis of resectable hepatocellular carcinoma. 摩尔杂志. 2018 12(1):89-113.

RESEARCH PROGRAMS AND AFFILIATIONS

Biochemistry and Molecular Biology

Biomedical Sciences Program

泌尿外科

研究兴趣

Cancer systems biology, 生物信息学, big data and survival prediction analyses, predictive and personalized medicine, computational genome and transcriptome biology, 非b DNA结构, RNA, DNA杂交, R-loops, G-quadruplexes, ncRNAs, clinical biomarker discovery and validation

教育利益

Bioinformatics, computational and statistical genomics, systems biology of cancer

ASSOCIATIONS / MEMBERSHIPS

American Association for Cancer 研究 (AACR), Active Member

教育

Additional Training: NIH, Bethesda MD, 2004, 生物信息学 and cancer genomics

博士: Moscow State University, Russia, 1984, biophysics

研究抽象

Current research projects and focus areas: computational and systems biology of cancer, genome and transcriptome integrity and instability, statistical genomics and 生物信息学, secondary nucleic acid sequence structures, RNA-DNA hybrids and computational R-loop biology, non-coding DNA and RNA, single cell transcriptome kinetics, 多样性, bifurcations in cell differentiation and proliferation, integrative sequence databases, big data and NGS data analytics strategies, quantitative oncoimmunology, methods for personalized cancer diagnostics and prognosis and non-invasive detection of malignancy, and the development of innovative methods of identification and validation of clinically relevant onco-markers.

出版物

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